1. The look-alike oval water drop refers to one of the water drops those combined to be a river of education. This is comparable with the merging of local institutions to be the Nakhon Phanom University. The brown and yellow colours represent the provincial colour and the University colour respectively.
2. The Lord Buddha Relic “That-Phanom” (Pra That Phanom) on a lotus refers to the worship of Pra That Phanom. Pra That Phanom is the provincial logo of Nakhon Phanom, and also represents the mentally fusion of tribal people in Nakhon Phanom.
3. The arches in four directions represent opportunities of education, allowing one to pursue knowledge.
4. The three blue water-wave lines pattern refers to the Mae Kong River, which run through many countries. This is comparable with the educational opportunities that are internationally open.
5. The seven lotuses pattern refers to the pattern found on the Pra That Phanom, which is the symbol of morality. These seven lotuses are comparable with the seven local institutions those merged to be the Nakhon Phanom University.
6. The golden (rice) spikes represent the growth and the harmony of the University group members that work toward the success of the University.
7. The lion base represents the stability and the sustainability of the University.